Is peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether safe during pregnancy?

Pregnancy-Safe Alternatives to peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether | VeriMom

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See also

• Is peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether safe for babies?
• Should I avoid peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether during pregnancy?
• What are pregnancy-safe alternatives to peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether?

Frequently asked questions

Is peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether safe during pregnancy?

No harmonised CLP (ECHA Annex VI) classification, no listing in EU Cosmetics Annex II or Annex III, and no SCCS/CIR or peer‑reviewed reproductive/developmental studies located for this exact INCI. Cosmetic ingredient databases (Cosmilee / Haut.de / Paula’s Choice / Cosmetic‑Info.jp) treat it as a PEG‑type polymer used as an emollient/solvent/emulsifier and cite PEG safety reviews (e.g., Fruijtier‑Pölloth PEG review) rather than repro concerns. Therefore there is no direct evidence to flag a reproductive hazard for pregnant users. ([cosmileeurope.eu](https://cosmileeurope.eu/nl/inci/ingredienten-2/19857/peg-23-poly-1-2-butanediol-21-propylene-glycol-dimethyl-ether/?utm_source=openai))

Is peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether safe while breastfeeding?

Same rationale as pregnancy: no harmonised H‑codes or EU Annex II/III entries for this specific ingredient, no CIR or SCCS safety opinion raising lactation/breastfeeding concerns, and no animal/human lactation transfer data found for this INCI. Absent specific data, parental guidance follows PEG‑derivative precedent (no repro warning). ([cosmileeurope.eu](https://cosmileeurope.eu/nl/inci/ingredienten-2/19857/peg-23-poly-1-2-butanediol-21-propylene-glycol-dimethyl-ether/?utm_source=openai))

Is peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether safe for baby skin?

No evidence of a reproductive mechanism or harmonised CMR classification for this INCI. Topical exposure for adults is expected to give negligible systemic absorption for a PEG‑type high‑MW polymeric ingredient; however infant skin (0–3 yr) has higher surface‑area:weight and an immature barrier, so exposure score is increased by +1 as per your scoring rules. No infant‑specific toxicology data were identified. ([cosmileeurope.eu](https://cosmileeurope.eu/nl/inci/ingredienten-2/19857/peg-23-poly-1-2-butanediol-21-propylene-glycol-dimethyl-ether/?utm_source=openai))

How does VeriMom score peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether?

VeriMom scores peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether at 39/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.

What are pregnancy-safe alternatives to peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether?

See our curated list of pregnancy-safe alternatives to peg-23 poly(1,2-butanediol)-21 propylene glycol dimethyl ether based on similar function and a no-known-risks safety band.