HIGH RISK
Should I Avoid n,n'-methylenebisacrylamide During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H340
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
Products built around the safer ingredients above, scored "no known risks" or "low risk".

Avero
100Avero Solid Deodorant

L'Occitane
100L´Occitane Powder To-mousse Facial Exfoliator

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Bitamin
100Bitamin Natural Deodorant N'orange

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Sustain Yourself
100Sustain Yourself Natural Deodorant

Dr Teals's
99Dr Teals's Aluminum Free Deodorant Charcoal

HappySoaps
99Happysoaps Neutraal

900care
99Déodorant stick parfum embruns

bareMinerals
99Complexion Rescue Tinted Hydrating Gel Cream Broad Spectrum SPF 30
Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to n,n'-methylenebisacrylamide | VeriMom
Ingredients — Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
See also
FAQ
- Is n,n'-methylenebisacrylamide safe during pregnancy?
- There are peer‑reviewed developmental toxicity studies in mice reporting decreased fetal body weight and increased fetal variations with N,N'-methylenebisacrylamide (110-26-9), indicating suspected developmental hazard (NOAEL for developmental toxicity reported at 3 mg/kg/day; adverse effects at higher doses). No harmonised CLP (Annex VI) reproductive classification was identified. For typical topical cosmetic use, dermal exposure/absorption from finished products is expected to be negligible. (Toxicological Sciences 1998; ECHA substance information; product SDSs/MSDSs reporting reproductive hazard category in supplier documents).
- Is n,n'-methylenebisacrylamide safe while breastfeeding?
- Same basis as pregnancy: animal developmental/reproductive studies show suspected developmental toxicity. There are no data showing transfer into human milk; for normal topical cosmetic use, exposure to a nursing infant via maternal milk is expected to be negligible. No authoritative cosmetic‑safety body (CIR/SCCS) reproductive clearance for this specific compound was located.
- Is n,n'-methylenebisacrylamide safe for baby skin?
- The hazard evidence (mouse developmental toxicity) supports a suspected reproductive/developmental hazard. Dermal exposure of infants (0–3 yr) is of greater concern than for adults because immature skin has higher surface‑area‑to‑weight and higher relative uptake; while adult topical cosmetic exposure is expected to be negligible, per the scoring rules infant exposure is increased by +1 when measurable absorption cannot be excluded. There are no infant‑specific toxicity data identified.
- How does VeriMom score n,n'-methylenebisacrylamide?
- VeriMom scores n,n'-methylenebisacrylamide at 39/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to n,n'-methylenebisacrylamide?
- See our curated list of pregnancy-safe alternatives to n,n'-methylenebisacrylamide based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.